What You Need to Know about Encapsulating Liquids

Capsuline Liquid CapsEncapsulating Liquids is an Art and a Science

Although most liquids can be encapsulated in either a gelatin or vegetarian capsule, the reality is that encapsulating liquids is often an art and a science. The results depend heavily on the formulation, the quality of the formulation, and a range of production-related variables.

This is why it is always best to order a small quantity of capsules and do some testing before you pull the trigger on a large capsule order. Until you test it, it’s hard to predict how your formulation and equipment will perform.

The Different Capsule Types

In determining which type of capsule is best for your liquid encapsulation needs, you first need to understand some of the basic benefits that each provides:

  • Gelatin Capsules have been the industry standard for decades. They offer the fastest disintegration time, and come in the broadest range of colors. They can be used for encapsulating powders and liquids, but are not always the best choice for oils. Because they are derived from animal products, they are not suitable for all diets.
  • Vegetarian Capsules are 100% plant derived, so they are suitable for most diets. Vegetarian capsules’ greater rigidity makes them particularly well-suited for liquids, and their stability characteristics make them the best choice for oils. They can be used for powders as well. Vegetarian capsules take a few minutes longer to disintegrate than gelatin capsules.
  • Enteric Capsules are vegetarian capsules that have a pH-sensitive polymer incorporated into the shell. This makes them acid-resistant by design. Enteric capsules pass through the stomach intact, and then disintegrate one to two hours later when they reach the small intestine.
  • Flavored Capsules are gelatin capsules that have delicious flavors and pleasing matching scents. They offer all the same other benefits as other gelatin capsules.

What’s the Best Choice – Gelatin or Vegetarian?

While you can encapsulate liquids in gelatin capsules, it can be tricky. For successful results, the formulation must have the right viscosity, and the capsule must be banded.*

HPMC vegetarian capsules are much more tolerant of your formulation. The more recommended option is to use a banded HPMC capsule to encapsulate liquids or oils.

Still Have Questions? We’re Here To Help!

Give us a call at 866.536.2277 or drop us an email. We’ll be happy to discuss your encapsulation needs. Ready to purchase your capsules? Head on over to Capsuline.com for the best selection of empty capsules in the industry.

* “Banding” refers to a process whereby the filled capsule is rolled through a liquid bath of gelatin (or HPMC, in the case of vegetarian capsules), resulting in a ring of material sealing the seam between the body and cap.

A Better Way To Give Your Pet Meds – Flavored Capsules

Flavored Capsules for Pets: A Great Solution for a Significant Problem

Pill Your Pet With Flavored Capsules If you’ve ever tried giving a pill to a pet, you know that pets do not like taking medication. Because standard capsules and pills do not smell or taste like “food,” most dogs and cats refuse to swallow them. Instead they run away, refuse to open their mouths, eat the food that the capsule is “disguised” in and then spit out the capsule, and so forth.

Often, out of desperation, pet owners resort to force feeding, which can be harmful in and of itself. Prying apart a pet’s jaws and shoving something down its throat (without getting bitten by the pet in the process) is stressful for the pet owner and frightening and painful for the pet.

Luckily, there is a better way.

Flavored Capsules for Pets Turn “Meds” into “Treats”

Available only from Capsuline, flavored capsules for pets make it easy to give capsules to pets. These unique gelatin capsules are currently available in three flavors that pets love: beef, chicken and bacon. Plus, there are more flavors under development.

Because these capsules both smell and taste like foods that pets love, pets happily ingest their medicine and then beg for more. By transforming medicines into “treats,” flavored capsules for pets eliminate the need for force feeding, disguising the capsule in a ball of food, and other often-unsuccessful ways to pill a pet.

Available in Three Sizes

Flavored capsules for pets can be used to encapsulate powders, liquids, extracts and oils. They are compatible with all capsule-filling machines. All three flavors are available in the three most popular capsule sizes for the veterinary market:

Size Volume Overall Closed Length
0 .68 ml 21.6 mm
1 .48 ml 19.4 mm
3 .27 ml 15.7 mm


These are premium-quality products made from BSE-free 100% bovine hide pharmaceutical grade gelatin in a cGMP and FDA-approved facility. In fact, these capsules are made to such a high standard that they are safe for human consumption as well!

To purchase these flavored capsules for pets, click here.

Top Benefits of Enteric Coated Capsules

Enteric Coated CapsulesWhether they’re gelatin capsules (i.e. gel caps) or vegetarian capsules, most capsules are designed to dissolve in the stomach. But sometimes there are benefits to using a capsule that does not dissolve until it reaches the small intestine. This is what Enteric Coated Capsules are designed for.

What are Enteric Coated Capsules?

Enteric Coated Capsules are capsules that have been coated with an acid resistant material that does not break down in the acidic environment of the stomach. Instead, they pass through the stomach intact, and are only activated when in an alkaline environment with a pH of 5.5 or higher – i.e. when they reach the small intestine.

It is important to note that Enteric Coated Capsules are acid-resistant by design. They are not the same as the “acid resistant” products that are simply vegetarian capsules with 5% gellan gum; these other products fail to meet pharma dissolution requirements. Enteric Coated Capsules have a pH-sensitive polymer incorporated into the shell. This advanced polymer will only dissolve at a pH of 5.5 or higher.

What are the Benefits of Enteric Coated Capsules?

For some formulations, Enteric Coated Capsules are an ideal choice. This is because they:

  • Will not dissolve in the mouth – Enteric Coated Capsules are perfect for drugs that are acid-activated, as they prevent the drug from activating in the mouth or esophagus.
  • Will not irritate the stomach – Many drugs, such as aspirin, can irritate the stomach. Because they pass through the stomach intact, Enteric Coated Capsules avoid this problem.
  • Can preserve enzyme activity Most tablets break down in the highly acidic environment of the stomach. Unfortunately, depending on the product’s formulation, this acidic environment can also negatively impact the desired enzyme activity. Enteric Coated Capsules protect the enzymes so that they can be absorbed, at their highest activity levels, in the small intestine.
  • Take longer to dissolve – While most capsules dissolve within 15 minutes, Enteric Coated Capsules do not dissolve until approximately one to two hours after ingestion, when they reach the small intestine. These capsules can therefore provide a “timed-release” affect.

Where can I purchase Enteric Coated Capsules?

Capsuline.com has a wide variety of enteric capsules at very competitive prices.

How To Make Your Own Supplements by Labdoor

LabDoor Make Your Own SupplementsWhether you’re looking for a custom product to fit your dietary restrictions or just want to save a few dollars on branded products, you should consider making your own supplements.

Our friends at LabDoor created a do it yourself tutorial on making your own supplements. Check out the article to receive a 10% off promo code for all Capsuline products! Make Your Own Supplements

Inspired to fill your own supplements?

Visit us here at Capsuline to get started with our herbs and supplements, pharmaceutical-grade, BSE-free, Kosher certified empty capsules and efficient filling machines.

Toxic Capsules Found On Sale in China – 11 Arrested

Toxic Capsule Factory Found in China, 11 ArrestedImage Credit - Daily Post

“Not Again”… that’s what we here at Capsuline said upon seeing this Reuters post entitled “China arrests 11 over toxic capsule factory”. Seems they were manufacturing gelatin capsules that contained a high level of chromium which is very toxic to humans and pets alike. This is usually the result of the use of “industrial grade” gelatin which, while less expensive to acquire, is not fit for human consumption.

At Capsuline, every capsule we manufacture is made with BSE-free100% bovine pharmaceutical gelatin to give you an extra measure of safety that not all manufacturers provide. Our gel caps are both Kosher Pareve and Halal certified and made in a cGMP and FDA-approved facility here in North America.

View our entire selection of Gelatin, Vegetarian, and Flavored capsules at Capsuline.com today.

Capsuline Featured in Cannabis Now

Once Brave Mykayla tried our flavored capsules while taking her cannabis oil to treat her leukemia, she was instantly happier and had a much easier time taking her medication. We are very lucky to help such an amazing girl and she her story was recently featured in Cannabis Now Magazine where she talked about her experience with our capsules and how it has helped her treatment process.

Check out the entire article here and learn more about this amazing story and make sure to LIKE Brave Mykayla on Facebook.

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Gelatin in the News

Gel CapsulesEarlier this week, reports of a bad batch of gelatin capsules surfaced in Asia claiming the German company Gelita sold over 30 tons of gelatin made from “discarded leather scraps” to various Chinesecompanies. Companies that use this gelatin to make products like gummy candies and medicine have
distanced themselves from Gelita, which has people taking more of an interest in knowing where their food comes from.

 In response, Capsuline would like to assure all of our gelatin is 100% bovine from approved gelatin suppliers, and Capsuline does not use the gelatin mentioned in this article in its products.

To learn more about the story, you can read it here.



Brave Mykayla takes cannacaps internationally!

A cancer diagnosis is painful for any family, when it affects a child it is that much more debilitating. Mykayla Comstock aka Brave Mykayla was diagnosed with leukemia in May 2012. She undertook typical cancer treatments such as chemotherapy and when that did not put her in remission radiation was the next suggested step.

Mykayla’s parents, Erin Purchase and Brandon Kenzler, chose to take a different option. They decided to use cannabis oil to fight her cancer. Erin and Brandon felt it was the best way to treat their daughter.

“If we didn’t use cannabis oil for our daughter she’d have to use opiate medications such as Oxycodone or Percocets” said Erin.

Our very own flavored capsules were chosen to treat Mykayla in which she fills her cannabis oil in her favorite bubblegum flavor, that helps with the taste in her mouth. We couldn’t be happier with Mykayla’s progress; within a week of treatment her cancer had went into remission!

Australian 7News recently did a story covering Mykayla and you can check out the video clip here and see why this brave little girl’s story should be receiving international attention.

For more information on Mykayla’s story or all of our different flavored capsules that she uses, please visit our website or reach out to us on Facebook, Twitter or Pinterest and we will gladly answer any questions you may have!



Capsuline is now on Pinterest!

We are happy to announce that we have expanded our fight against cancer!

You can now follow your favorite source for empty capsules on!  Follow CapsulineInc’s boards and learn invaluable tips on how to improve your overall health and wellness.  Brave Mykala’s heroic story contributes to our boards on strong cancer survivors.  We will also be featuring boards that give you information on the benefits of our many herbal products, different health recipe’s, nutrition, inspirational stories and other fun boards. We will be updating our boards daily, so if you know anyone that may be on Pinterest and interested in learning more about our products or our #CapsuleCares campaign, feel free to reach out and re-pin away!

Support our fight against cancer with the hashtag: #CapsuleCares!

Happy pinning to all our fans; we look forward to sharing with you!

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Olivia enjoys her strawberry capsules from #CapsuleCares

Meet Olivia, a young girl that has been using our flavored capsules which help break up her medicine and also allow her to take her pills all at once rather than multiple times a day. She has learned new ways of taking the pills after talking with her friend Brave Mykayla, who has been using our flavored capsules to fill her cannabis oil, to treat her cancer. These capsules help Oliva take her daily dose of medicine and also allow her to do so pain free and with a better taste in her mouth.

We are very excited to help Oliva and can’t wait to hear about her progress moving forward. We continue to seek new individuals who may benefit from our #CapsuleCares campaign and will continue to donate 1,000 flavored capsules to the Phoenix Tears Foundation for every 5,000 flavored capsules we sell.

If you know of anyone that may benefit from our flavored capsules or want to learn more about our campaign, please visit us on Facebook, Twitter or stop by our website for more details!

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